A Case of Adenocarcinoma Ex Pleomorphic Adenoma with Tumor Thrombus of Submandibular Gland

Korean Journal of Head & Neck Oncology 2010;26(2):216-220.
Published online November 30, 2010.

Chul Kwon;Choel Eon Park;Il Ho Shin;Young Gyu Eun;Kee Hwan Kwon

악하선에 발생한 종양 혈전을 동반한 다형선종유래 선암종

권 철;박철언;신일호;은영규;권기환

Abstract

Carcinoma ex pleomorphic adenoma is rare, aggressive, poorly understood malignancy that occurs in the salivary glands. The patient was 70-year-old male presenting ovoid elevated submandibular mass that has been present for 30 years and rapid growing for 6 months. The initial cytologic finding by fine needle aspiration biopsy showed highly malignant cells and the radiologic finding revealed a 3.6×3.7×4.8cm sized mass with cervical lymphadenopathy. After wide excision of submandibular gland and modified radical neck dissection, the histologic examination revealed that tumor was composed partly of a benign pleomorphic adenoma and partly of an adenocarcinoma component with areas of calcification and frequent angiolymphatic invasion. We present a rare case of adenocarcinoma ex pleomorphic adenoma with tumor thrombus in the submandibular gland.

Key Words: Carcinoma ex pleomorphic adenoma, Submandibular gland, Tumor thrombus