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Korean Journal of Head & Neck Oncology 1999;15(2):182-188.
Published online November 30, 1999.
Patterns of Failure after Combined Surgery and Radiation Therapy for Malignant Tumors of the Parotid Gland -Analysis of Treatment Results According to Pathologic Type-
Sang Wook Lee;Sei Kyung Chang;Gwi Eon Kim;Chang Ok Suh;Jin sil Seong;Chang Geol Lee;Ki Chang Keum;Cheong Soo Park;Eun Chang Choi
근치적수술과 술후방사선치료를 받은 이하선 악성종양 환자의 치료실패 양상 병리학적 유형에 따른 결과를 중심으로
To investigate the treatment results' and patterns of failure according to the pathologic type of the parotid malignancy who were treated with radical sugery and postoperative radiation therapy. Materials and Methods: Fifty-two patients with various type of the parotid malignancy, who were treated with combined radical surgery and post-operative irradiation at Yonsei Cancer Center, between 1981 and 1995, were retrospectively reviewed after completion treatment, all but one patients were follow up with the median follow up period of 49 months.
We found that pathologically confirmed neck node metastasis rate was 28.8% all case and level II was most common site. Overall failure rate was 26.9%, local recurrence rate was 13.5%, node failure rate was 7.7%, and distant failure rate was 5.8%. Five-year disease free survival rate was 70.9%, and overall survival rate was 73.8%. Recurrence rate was low in adenoid cystic carcinoma and acinic cell carcinoma. However distant metastasis was very high in undifferentiated carcinoma. Local recurrence was main pattern of failure in mucoepidermoid carcinoma and nodal failure was frequently observed in adenocarcinoma.
Individualized treatment plan may be required to improve a treatment outcome by pathologic subtype of the parotid malignancy.
Key Words: Parotid gland malignancy, Surgery, Radiotherapy
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