A Case of Primary Large B-cell Lymphoma of Larynx Presenting as Supraglottic Mass

Korean Journal of Head & Neck Oncology 2015;31(1):31-33.
Published online May 30, 2015.

Jeon Ha Choi;Choon Dong Kim;Yoon Jung Kim;Seung Woo Kim

성문상부 종물 양상의 일차성 후두 Large B세포 림프종 1예

최전하;김춘동;김윤정;김승우

Abstract

The extranodal non-Hodgkin lymphoma is uncommonly occurred in larynx, accounting for less than 1% of all laryngeal neoplasm. In general, the laryngeal lymphoma is appeared as submucosal mass without mucosal ulcer-ation and is most commonly found in supraglottis. The primary laryngeal lymphoma constitute a diagnostic chal-lenge because they are characterized by absence of clinical and gross differential criteria, compared with squamous cell carcinoma (SCC). We encountered a 74-year-old man with hoarseness and lump sensation in the throat. On di-rect laryngoscope, multiple ulcerative and exudative mass in glottis and supraglottic areas were observed. The pa- tient was finally diagnosed as large B-cell lymphoma through the laryngeal microsurgery. He received radiation therapy and there is no evidence of recurrence. Although the laryngeal mass has superficial mucosal change, pri- mary laryngeal lymphoma must be included in the differential diagnosis.

Key Words: LarynxㆍLymphoma