Clinical Factors Associated with Recurrence of Nasopharyngeal Carcinoma

Korean Journal of Head & Neck Oncology 2014;30(1):5-9.
Published online May 30, 2014.

Sohea Ok,;Soo-Hyung Lee;Sunjin Hwang;Min-Woo Park;Jae-Gu Cho;Seung-Kuk Baek;Soon-Young Kwon;Kwang-Yoon Jung;Jeong-Soo Woo

비인두암의 재발에 연관된 임상적 지표

옥소혜;이수형;황선진;박민우;조재구;백승국;권순영;정광윤;우정수

Abstract

Background and Objectives：The objective of this study was to investigate clinical factors associated with re-currence of nasopharyngeal carcinoma(NPC). Materials and Methods：We performed a retrospective review of 112 diagnosed as nasopharyngeal carcinoma, treated concurrent chemo-radiotherapy(CCRT) and had complete response from March 1, 1995, to March 31, 2012. Results：Of the recurrent NPC patients, patients received 2nd line chemotherapy had more recurrence within 2 years(p=0.010). Especially, patients received 2nd line chemo-therapy longer than 4 months tend to have recurrence early(p=0.035). Other factors are not different between re-current and non-recurrent NPC patients. Conclusion：The presence and the duration of 2nd line chemotherapy are associated with early recurrence.

Key Words: Nasopharyngeal carcinoma, Recurrence, Clinical factor