Utility of FDG PET/CT Scans on Extracapsular Spread of Squamous Cell Carcinoma in the Larynx

Korean Journal of Head & Neck Oncology 2012;28(2):118-121.
Published online November 30, 2012.

Young-Hoon Joo유이령;Ie-Ryung Yoo;Kwang-Jae Cho;Jee-Nam Song;Dong-Joon Yoo;Ho-Suk Lee;Min-Sik Kim

후두 편평상피암종의 림프절 피막외 침범에 대한 FDG PET/CT 영상의 유용성

주영훈;조광재;송지남;유동준;이호석;김민식

Abstract

Backgrounds：To evaluated the use of FDG PET/CT for the identification of extracapsular spread(ECS) with histologic correlation in laryngeal cancer. Methods：We reviewed 79 medical records of patients who under-went of FDG PET/CT for laryngeal cancer before surgery. Results：ECS was present in 41.9%(18/43) dis-sected necks and in 34.5%(20/58) dissected cervical levels. There was a significant difference in the SUVmax between cervical lymph nodes with ECS and without ECS(6.39±4.53 vs. 1.19±1.64, p＜0.001). The cut-off value for the SUVmax for differentiating with ECS from without ECS was 2.8 with the sensitivity of 85.7% and the specificity of 85.6%. Conclusion：The median SUVmax cut-off values of FDG PET/CT higher than 2.8 was associated with greater risk cervical lymph node metastasis with ECS in patients with laryngeal cancer.

Key Words: Squamous cell carcinoma, Larynx, Lymphatic metastasis, Positron-emission tomography