Radiation Therapy of Squamous Cell Carcinoma of the Maxillary Sinus

Korean Journal of Head & Neck Oncology 1995;11(2):145-152.
Published online November 30, 1995.

Eun Ji Chung;Gwi Eon Kim;Chang Geol Lee;Woo Cheol Kim

상악동 편평상피암의 방사선치료

정은지;김귀언;이창걸;김우철

Abstract

A retrospective analysis was performed to ascertain the relationship between the treatment modalities and their treatment results. From July 1980 to June 1993, 115 patients with squamous cell carcinoma of the maxillary sinus were: treated at the Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University. There were 88 men and 27 women with median age of 57 years. According to AJCC TNM system of 1992. eight patients of T2, 54 patients of T3 and 53 patients of T4 were available, respectively. Cervical lymph node metastases at diagnosis was observed in 11 patients. 87 patients were treated with radiotherapy and 28 patients were treated with combination of surgery and radiotherapy. The overall 5 year survival rate was 32 %, patients that were treated with radiotherapy alone had a 5 year survival rate 24.3 % and patients who were treated with combination of surgery and radiation therapy had a 5 year survival rate of 52.8 % (p<0.05). Combination of surgery and radiotherapy resulted in a better treatment modality for squamous cell carcinoma of the maxillary sinus. Improved radiotherapy technique and development of multimodality treatment are needed to improve the local control and the survival rate in patients with advanced maxillary sinus carcinoma.

Key Words: Maxillary sinus carcinoma, Squamous cell carcinoma, Radiotherapy, Surgery, Chemotherapy