A Case of Primary Adenosquamous Carcinoma of the True Vocal Fold Mimicking Atypical Squamous Cell Proliferation

Korean Journal of Head & Neck Oncology 2016;32(2):19-22.
Published online November 30, 2016.

Ju Yeon Kim;Mi Sun Chun;Soo Yeon Jung;Han Su Kim

비정형 편평세포 증식으로 오인된 진성대의 원발성 선편평세포암종

김주연;천미선;정수연;김한수

Abstract

Adenosquamous carcinoma (ASC) of the larynx is very rare malignancy which has well defined two distinctive pathological features, an adenocarcinoma and a squamous cell carcinoma (SCC). Diagnosis of ASC by endoscopic biopsy is challenging due to small amount of harvested tissue. ASC has a worse prognosis than SCC with an early lymph node metastasis and a distant dissemination. We experienced a rare case of vocal fold ASC which was initially misdiagnosed as atypical squamous cell proliferation at frozen biopsy. We reported this case with a literature review.

Key Words: Adenosquamous carcinoma, Vocal cords, Atypical squamous cells