| Combination Therapy for Advanced Maxillary Sinus Cancers |
|
Seung Ho Cho;Hyung Tae Kim;Min Sik Kim;Hoon Kyo Kim;Sei Chul Yoon;In Ah Kim;Woo Jeong Yoo;Sung Won Kim |
| 진행된 상악동암의 병용치료 |
|
조승호;김형태;김민식;김훈교;윤세철;김인아;유우정;김성원 |
|
|
|
|
| Abstract |
Background: Cancers of the maxillary sinuses are not common and are the most difficult head and neck malignancies in which to make an early diagnosis.
Objectives: This reports was conducted to evaluated the efficacy of combination therapy and the relationship between the treatment modalities and their outcome of maxillary sinus cancers.
Materials and Methods: We retrospectively analyzed a clinical datas of 46 patients who were treated at the department of Otolaryngology-Head and Neck Surgery. The Catholic University of Korea over 10 years between 1987 and 1996.
Results
According to AJCC TNM system, 35 patients presented with T4, 10 with T3, one with T1. Two patients were treated with radiotherapy alone, 4 patients with chemotherapy alone, 17 patients with radiotherapy and chemotherapy, 23 patients with combination of surgery, radiotherapy and chemotherapy. The overall 5 years survival rate for combination therapy group were 57%, but 23 patients treated with the other treatment modalities all died within 2 years except two cases with chemotherapy and radiotherapy or radiotherapy alone. There was a statistical trend for better survival and local control in those patients treated with combination therapy than others(p<0.05).
Conclusion
The results of this study suggest that it may be possible to acheive better results with aggressive combination treatment including surgery in advanced cases and to avoid orbital excentration in patients with orbital invasion. |
| Key Words:
Combination therapy, Maxillary sinus cancer, Chemotherapy, Radiotherapy |
|
PDF Links
Full text via DOI
Download Citation
